18F-Fluciclovine PET/CT to Distinguish Radiation Necrosis from Tumor Progression in Brain Metastases Treated with Stereotactic Radiosurgery
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چکیده
منابع مشابه
Non Tumor Perfusion Changes Following Stereotactic Radiosurgery to Brain Metastases
PURPOSE To evaluate early perfusion changes in normal tissue following stereotactic radiosurgery (SRS). METHODS Nineteen patients harboring twenty-two brain metastases treated with SRS were imaged with dynamic susceptibility magnetic resonance imaging (DSC MRI) at baseline, 1 week and 1 month post SRS. Relative cerebral blood volume and flow (rCBV and rCBF) ratios were evaluated outside of tu...
متن کاملRecurrent radiation necrosis in the brain following stereotactic radiosurgery.
Harvard Medical School, Boston, Massachusetts Department of Neurosurgery, Dana-Farber/Brigham & Women’s Cancer Center, Boston, Massachusetts Department of Pathology, Dana-Farber/Brigham & Women’s Cancer Center, Boston, Massachusetts York Hospital Oncology, York, Maine Department of Medical Oncology, Dana-Farber/Brigham & Women’s Cancer Center, Boston, Massachusetts Department of Radiation Oncol...
متن کاملStereotactic radiosurgery for brain metastases.
Worldwide, approximately 100,000 patients have undergone stereotactic radiosurgery for a variety of intracranial lesions, of which brain metastases represent the most common treatment indication. This article summarizes the major issues surrounding the management of brain metastases, and also analyzes 21 independent reports of Gamma Knife- or linear accelerator-based radiosurgery, representing ...
متن کاملThe prognostic value of tumor necrosis in patients undergoing stereotactic radiosurgery of brain metastases
BACKGROUND This retrospective study investigated the outcome of patients with brain metastases after radiosurgery with special emphasis on prognostic impact of visible intratumoral necrosis on survival and local control. METHODS From 1998 through 2008, 149 patients with brain metastases from solid tumors were treated with stereotactic radiotherapy at Luebeck University. Median age was 58.4 ye...
متن کاملBevacizumab as a treatment for radiation necrosis of brain metastases post stereotactic radiosurgery.
BACKGROUND Cerebral radiation necrosis (RN) is a difficult to treat complication of stereotactic radiosurgery (SRS) that can result in progressive neurologic decline. Currently, steroids are the standard of care treatment for brain RN despite their adverse effect profile and limited efficacy. The purpose of this study was to evaluate the treatment efficacy of cerebral RN to bevacizumab in patie...
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ژورنال
عنوان ژورنال: International Journal of Radiation Oncology*Biology*Physics
سال: 2020
ISSN: 0360-3016
DOI: 10.1016/j.ijrobp.2020.07.2033